Our Methodology

Editorial Process

Each peptide profile and guide goes through the following editorial workflow before publishing:

1. Source review. An editor compiles the strongest available evidence base — PubMed-indexed peer-reviewed studies, ClinicalTrials.gov trial registrations, FDA / EMA / MHRA approval letters where applicable, and vendor Certificates of Analysis (COAs) for research-chemical compounds.
2. AI-assisted draft. An AI system drafts the initial research summary using only the source material gathered in step 1. Drafts are explicitly prohibited from inventing studies, fabricating sample sizes, or making prescriptive claims about human use.
3. Human verification. An editor verifies every numerical claim, study citation, and legal-status statement against the original source. Anecdotal user reports are clearly labeled as such.
4. Disclaimer audit. Every page must include the regulatory framing — research-only use, not medical advice, not approved for human consumption in major jurisdictions where applicable.
5. Publish. Reviewed guides go live with an explicit publication date and a “last updated” timestamp on every page.

What We Cover — And What We Don't

Sources We Use

We draw from the following primary sources, in roughly this order of priority:

• PubMed — indexed peer-reviewed biomedical research; the gold standard for evidence assessment.
• ClinicalTrials.gov — ongoing and completed clinical trial registrations with sample sizes, endpoints, and (where reported) results.
• FDA Orange Book — approval status of prescription drug products in the US.
• EMA medicines database — equivalent approval status across the EU.
• MHRA Products — UK medicines register.
• TGA Australia — Australian therapeutic goods register.
• Vendor-supplied Certificates of Analysis (COAs) — third-party HPLC / mass-spec purity testing reports for research-chemical peptides. Vendors who do not publish COAs are not linked.

Conflict of Interest Policy

Peptide Guides earns affiliate commissions when readers purchase from vendors we link to. Affiliate relationships do not influence inclusion, ordering, scoring, or written verdicts. We do not accept paid placements, sponsored reviews, or pay-to-play rankings of any kind. Where a vendor declines to publish a Certificate of Analysis, that vendor is not linked regardless of commission rate. See our affiliate disclosure for the operational details.

Corrections & Updates

When we discover or are notified of a factual error, we update the page promptly and note the change. Major content updates refresh the “last updated” date on the page. Methodology changes (this document) are dated above. If you spot a claim you can't verify in the cited sources, please email us at editorial@peptideguides.org with the page URL and the specific claim — we'll investigate and correct.

Editorial Team

Peptide Guides is published by an editorial team that includes contributors with backgrounds in clinical research, biochemistry, and science writing. We deliberately do not publish individual author bylines on health-adjacent content because we do not want a single named author to be misread as a clinical authority. The methodology above is what we ask readers to evaluate — not any individual editor's credentials.

If you are a researcher with subject-matter expertise in any peptide we cover and would like to contribute or review, please get in touch.